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Indole alkaloids are responsible for toxicity of
Phalaris pastures to sheep and cattle [l-3]. Several of these alkaloids are present in various species of Gramineae, Leguminosae and other plant families [4]. Simple indole bases such as 3-N,Ndimethylaminomethylindole (gramine)
5-methoxy-N,N-dimethyltryptamine (MOM2T, 2), 5- methoxytryptamine (MOT, 3) and N,-methyltryptamine (MT, 4)

...total alkaloid content varies between 0.02-1.19 of dry wt in Phalaris arundinacea [7]
and gramine concentration may reach up to 7 mmol/kg fr. wt in barley [S],

..Several plant secondary metabolites are thought to protect plants against insects and patho- gens. For example, hydroxamic acids from Gramineae have been suggested to protect wheat and maize against the European corn borer.

Vzeto iz: wikipedia.it - hidroskamska/e kisline
"Vedno znani po svoji lastnosti selektivne kelacije kovin, ki tvorijo stabilne snovi, zlasti s Cu2 +, Fe3 +, V5 +, UO22 +. Študirali so jih tudi za uresničevanje polimernih verig s kelatnimi lastnostmi, ki se uporabljajo pri selektivnem odstranjevanju težkih kovin [2] [3] Nekatere hidroksamske kisline, kot so SAHA, Vorinostat, PXD101 in Belinostatin, LAQ824 / LBH589 in trihostatin A, so inhibitorji HDAC in imajo lastnost da preprečijo rakaste tvorbe ".

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